Biology Reference
In-Depth Information
153. Nishina K, Unno T, Uno Y, Kubodera T, Kanouchi T, Mizusawa H, Yokota T (2008) Efficient
in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol. Mol Ther
16:734-740
154. Volkov AA, Kruglova NS, Meschaninova MI, Venyaminova AG, Zenkova MA, Vlassov VV,
Chernolovskaya EL (2009) Selective protection of nuclease-sensitive sites in siRNA pro-
longs silencing effect. Oligonucleotides 19:191-202
155. Turner JJ, Jones SW, Moschos SA, Lindsay MA, Gait MJ (2007) MALDI-TOF mass spectral
analysis of siRNA degradation in serum confirms an RNAse A-like activity. Mol Biosyst
3:43-50
156. Sorrentino S (1998) Human extracellular ribonucleases: multiplicity, molecular diversity and
catalytic properties of the major RNase types. Cell Mol Life Sci 54:785-794
157. Qiu L, Moreira A, Kaplan G, Levitz R, Wang JY, Xu C, Drlica K (1998) Degradation of ham-
merhead ribozymes by human ribonucleases. Mol Gen Genet 258:352-362
158. Bartlett DW, Davis ME (2007) Effect of siRNA nuclease stability on the in vitro and in vivo
kinetics of siRNA-mediated gene silencing. Biotechnol Bioeng 97:909-921
159. Hoerter JA, Krishnan V, Lionberger TA, Walter NG (2011) siRNA-like double-stranded
RNAs are specifically protected against degradation in human cell extract. PLoS One
6:e20359
160. Song E, Lee SK, Dykxhoorn DM, Novina C, Zhang D, Crawford K, Cerny J, Sharp PA,
Lieberman J, Manjunath N et al (2003) Sustained small interfering RNA-mediated human
immunodeficiency virus type 1 inhibition in primary macrophages. J Virol 77:7174-7181
161. Fedorov Y, Anderson EM, Birmingham A, Reynolds A, Karpilow J, Robinson K, Leake D,
Marshall WS, Khvorova A (2006) Off-target effects by siRNA can induce toxic phenotype.
Rna 12(7):1188-1196
162. Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C (2004) Innate antiviral responses
by means of TLR7-mediated recognition of single-stranded RNA. Science 303:
1529-1531
163. Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H,
Bauer S (2004) Species-specific recognition of single-stranded RNA via toll-like receptor 7
and 8. Science 303:1526-1529
164. Diebold SS, Massacrier C, Akira S, Paturel C, Morel Y, Reis e Sousa C (2006) Nucleic acid
agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides. Eur J
Immunol 36:3256-3267
165. Judge AD, Bola G, Lee AC, MacLachlan I (2006) Design of noninflammatory synthetic
siRNA mediating potent gene silencing in vivo. Mol Ther 13:494-505
166. Kariko K, Buckstein M, Ni H, Weissman D (2005) Suppression of RNA recognition by Toll-
like receptors: the impact of nucleoside modification and the evolutionary origin of RNA.
Immunity 23:165-175
167. Cekaite L, Furset G, Hovig E, Sioud M (2007) Gene expression analysis in blood cells in
response to unmodified and 2¢-modified siRNAs reveals TLR-dependent and independent
effects. J Mol Biol 365:90-108
168. Flatekval GF, Sioud M (2009) Modulation of dendritic cell maturation and function with
mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase.
Immunology 128:e837-e848
169. Hamm S, Latz E, Hangel D, Muller T, Yu P, Golenbock D, Sparwasser T, Wagner H, Bauer S
(2009) Alternating 2¢-O-ribose methylation is a universal approach for generating non-stim-
ulatory siRNA by acting as TLR7 antagonist. Immunobiology 215:559-569
170. Kariko K, Bhuyan P, Capodici J, Ni H, Lubinski J, Friedman H, Weissman D (2004)
Exogenous siRNA mediates sequence-independent gene suppression by signaling through
toll-like receptor 3. Cells Tissues Organs 177:132-138
171. Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baf fi JZ, Albuquerque
RJC, Yamasaki S, Itaya M, Pan YZ et al (2008) Sequence- and target-independent angiogen-
esis suppression by siRNA via TLR3. Nature 452:591-597
172. Manche L, Green SR, Schmedt C, Mathews MB (1992) Interactions between double-stranded
RNA regulators and the protein kinase DAI. Mol Cell Biol 12:5238-5248
Search WWH ::




Custom Search