Biology Reference
In-Depth Information
dimensional structure as that shown in Fig. 2-2 can be found in a standard
textbook, Lehninger Principles of Biochemistry (Nelson and Cox, 2000) and
at the website <http://www.rcsb.org/pdb/>.
Figure 2-2.
and
subunits of hemoglobin from Nelson and Cox (2000) with permission.
It is important to realize that the folded structure is not static. The
connecting loops or turns as well as the -helices can move around relative
to each other. The iron atom in the heme is also movable, depending on the
presence or absence of oxygen molecule.
EQUILIBRIUM BINDING OF MYOGLOBIN WITH OXYGEN
The reversible binding of myoglobin with oxygen can be represented as:
