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In-Depth Information
Table 11.5
Correlation between serum taurine and adiponectin or
leptin levels
Taurine
Adiponectin
Leptin
Taurine 1
Adiponectin 0.782**
a
1
Leptin 0.022 −0.156 1
a
Significant correlation was assessed by the Spearman correlation
(**
p
< 0.01)
Table 11.6
Correlation between serum taurine level and adipose tissue weight or lipid profiles
Relative
liver weight
Relative
E-fat weight
Relative
R-fat weight
Taurine
TG
TC
Taurine 1
TG 0.318 1
TC −0.642*
a
−0.049 1
Relative liver weight −0.762* −0.370 0.415 1
Relative E-fat weight 0.267 0.627* −0.288 −0.467 1
Relative R-fat weight 0.267 0.818** −0.097 −0.450 0.830** 1
a
Significant correlation was assessed by the Spearman correlation (*
p
< 0.05, **
p
< 0.01)
level and serum TC level (
p
< 0.05) and relative liver weight (
p
< 0.05), while there
was no significant correlation between serum taurine level and serum TG level or
relative E-fat and R-fat.
11.4
Conclusion
These results suggest that dietary taurine supplementation has beneficial effects on
serum total cholesterol and adiponectin levels in high-fat diet-induced obesity rats.
Acknowledgement
We thank the Dong-A Pharmaceutical Co. which donated taurine.
References
Brons C, Spohr C, Storgaard H, Dyerberg J, Vaag A (2004) Effect of taurine treatment on insulin
secretion and action, and on serum lipid levels in overweight men with a genetic predisposition
for type II diabetes mellitus. Eur J Clin Nutr 58(9):1239-1247
Du H, You JS, Zhao X, Park JY, Kim SH, Chang KJ (2010) Antiobesity and hypolipidemic effects
of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet. J Biomed
Sci 17(1):S42-S47
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