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CD4+T
0.4
0.35
0.3
0.25
350
weeks
300
310
320
330
340
Fig. 5.
Different drugeffectiveness with the same response function (
P
resp
) was ob-
served, which were
N
=0,
N
=1,
N
=4,
N
= 7 and no treatment locatingfrom the
top to the bottom in the figure respectively. The results here qualitatively simulated
mono-therapy and combined therapy.
CD4+T
1
0.8
0.6
0.4
0.2
weeks
100
200
300
400
500
600
Fig. 6.
Different response functions (
P
resp
) with the same drugeffectiveness (
N
=0)
were obtained, which were
P
resp
1
,
P
resp
2
and
P
resp
3
locatingfrom the top to the bottom
of the figure respectively.
P
resp
1 simulated the completely recoveringtherapy.
P
resp
2
and
P
resp
3 simulated the current HAART therapy. Vertical hash line represents the
startingof the therapy.
due to the limitation of infection, and only new resistant virus against drug
were left in the lattice (Fig. 7b). They developed and formed new virus sources
wave-like structures (Fig. 7c). Eventually, they evolved into AIDS phase. Only
wave-structures were left and covered the whole lattice. The steady states was
reached, in which the concentrations of each cell were kept relatively fixed and
patterns of structures were unchanged (Wolframs class II behaviour) (Fig. 7d).
