Biology Reference
In-Depth Information
Acknowledgments
The authors acknowledge the financial support from Fundação
para a Ciência e Tecnologia (FCT), Portugal (projects PTDC/
EBB-BIO/119501/2010 and PTDC/EBB-BIO/118615/2010)
and the FP7 EU project BrainCAV (HEALTH-HS_2008_222992).
A.C. Silva and P. Fernandes acknowledge the FCT for the Ph.D.
grants SFRH/BD/45786/2008 and SFRH/BD/70810/2010,
respectively.
References
1. McConnell MJ, Imperiale MJ (2004) Biology
of adenovirus and its use as a vector for gene
therapy. Hum Gene Ther 15(11):1022-1033
2. Tatsis N, Ertl HC (2004) Adenoviruses as vac-
cine vectors. Mol Ther 10(4):616-629
3. Dormond E, Perrier M, Kamen A (2009)
From the first to the third generation adenovi-
ral vector: what parameters are governing the
production
9. Bru T, Salinas S, Kremer EJ (2010) An update
on canine adenovirus type 2 and its vectors.
Viruses 2(9):2134-2153
10. Fallaux FJ, Bout A, van der Velde I, van den
Wollenberg DJ, Hehir KM, Keegan J, Auger
C, Cramer SJ, van Ormondt H, van der Eb AJ,
Valerio D, Hoeben RC (1998) New helper
cells and matched early region 1-deleted ade-
novirus vectors prevent generation of
replication-competent adenoviruses. Hum
Gene Ther 9(13):1909-1917
11. Schiedner G, Hertel S, Kochanek S (2000)
Efficient transformation of primary human
amniocytes by E1 functions of Ad5: genera-
tion of new cell lines for adenoviral vector pro-
duction. Hum Gene Ther 11(15):2105-2116
12. Cote J, Garnier A, Massie B, Kamen A (1998)
Serum-free production of recombinant pro-
teins and adenoviral vectors by 293SF-3F6
cells. Biotechnol Bioeng 59(5):567-575
13. Nadeau I, Gilbert PA, Jacob D, Perrier M,
Kamen A (2002) Low-protein medium affects
the 293SF central metabolism during growth
and infection with adenovirus. Biotechnol
Bioeng 77(1):91-104
14. Ferreira TB, Ferreira AL, Carrondo MJ, Alves
PM (2005) Two different serum-free media
and osmolality effect upon human 293 cell
growth and adenovirus production. Biotechnol
Lett 27(22):1809-1813
15. Maranga L, Aunins JG, Zhou W (2005)
Characterization of changes in PER.C6 cellu-
lar metabolism during growth and propaga-
tion of a replication-deficient adenovirus
vector. Biotechnol Bioeng 90(5):645-655
16. Mendonca RZ, Prado JCM, Pereira CA
(1999) Attachment, spreading and growth
of VERO cells on microcarriers for the opti-
mization of large scale cultures. Bioprocess
Biosyst Eng 20:565-571
17. Wu SC, Huang GY, Liu JH (2002) Production
of retrovirus and adenovirus vectors for gene
yield?
Biotechnol
Adv
27(2):133-144
4. Sheets RL, Stein J, Bailer RT, Koup RA,
Andrews C, Nason M, He B, Koo E, Trotter
H, Duffy C, Manetz TS, Gomez P (2008)
Biodistribution and toxicological safety of ade-
novirus type 5 and type 35 vectored vaccines
against human immunodeficiency virus-1
(HIV-1), Ebola, or Marburg are similar despite
differing adenovirus serotype vector, manufac-
turer's construct, or gene inserts. J
Immunotoxicol 5(3):315-335
5. Shott JP, McGrath SM, Pau MG, Custers JH,
Ophorst O, Demoitie MA, Dubois MC,
Komisar J, Cobb M, Kester KE, Dubois P,
Cohen J, Goudsmit J, Heppner DG, Stewart
VA (2008) Adenovirus 5 and 35 vectors
expressing Plasmodium falciparum circumspo-
rozoite surface protein elicit potent antigen-
specific cellular IFN-gamma and antibody
responses
in
mice.
Vaccine
26(23):
2818-2823
6. Kremer EJ, Boutin S, Chillon M, Danos O
(2000) Canine adenovirus vectors: an alterna-
tive for adenovirus-mediated gene transfer. J
Virol 74(1):505-512
7. Perreau M, Kremer EJ (2005) Frequency, pro-
liferation, and activation of human memory T
cells induced by a nonhuman adenovirus. J
Virol 79(23):14595-14605
8. Soudais C, Boutin S, Kremer EJ (2001)
Characterization of cis-acting sequences
involved in canine adenovirus packaging. Mol
Ther 3(4):631-640
