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therapy: a comparative study using microcar-
rier and stationary cell culture. Biotechnol
Prog 18(3):617-622
18. Kamen A, Henry O (2004) Development and
optimization of an adenovirus production pro-
cess. J Gene Med 6(Suppl 1):S184-S192
19. Silva AC, Peixoto C, Lucas T, Kuppers C,
Cruz PE, Alves PM, Kochanek S (2010)
Adenovirus vector production and purifica-
tion. Curr Gene Ther 10(6):437-455
20. Fernandes P, Peixoto C, Santiago VM, Kremer
EJ, Coroadinha AS, Alves PM (2013)
Bioprocess development for canine adenovirus
type 2 vectors. Gene Ther 20:353-360
21. Sandhu KS, Al-Rubeai M (2008) Monitoring
of the adenovirus production process by flow
cytometry. Biotechnol Prog 24(1):250-261
22. Segura MM, Puig M, Monfar M, Chillon M
(2012) Chromatography purification of canine
adenoviral vectors. Hum Gene Ther Methods
23:182-197
23. Peixoto C, Ferreira TB, Sousa MF, Carrondo
MJ, Alves PM (2008) Towards purification of
adenoviral vectors based on membrane tech-
nology. Biotechnol Prog 24(6):1290-1296
24. Croyle MA, Roessler BJ, Davidson BL,
Hilfinger JM, Amidon GL (1998) Factors that
influence stability of recombinant adenoviral
preparations for human gene therapy. Pharm
Dev Technol 3(3):373-383
25. Obenauer-Kutner LJ, Ihnat PM, Yang TY,
Dovey-Hartman BJ, Balu A, Cullen C,
Bordens RW, Grace MJ (2002) The use of
field emission scanning electron microscopy to
assess recombinant adenovirus stability. Hum
Gene Ther 13(14):1687-1696
26. Croyle MA, Cheng X, Wilson JM (2001)
Development of formulations that enhance
physical stability of viral vectors for gene ther-
apy. Gene Ther 8(17):1281-1290
27. Evans RK, Nawrocki DK, Isopi LA, Williams
DM, Casimiro DR, Chin S, Chen M, Zhu DM,
Shiver JW, Volkin DB (2004) Development of
stable liquid formulations for adenovirus-based
vaccines. J Pharm Sci 93(10):2458-2475
28. Cruz PE, Silva AC, Roldao A, Carmo M,
Carrondo MJ, Alves PM (2006) Screening of
novel excipients for improving the stability of
retroviral and adenoviral vectors. Biotechnol
Prog 22(2):568-576
29. Rexroad J, Wiethoff CM, Green AP, Kierstead
TD, Scott MO, Middaugh CR (2003)
Structural stability of adenovirus type 5.
J Pharm Sci 92(3):665-678
30. Altaras NE, Aunins JG, Evans RK, Kamen A,
Konz JO, Wolf JJ (2005) Production and for-
mulation of adenovirus vectors. Adv Biochem
Eng Biotechnol 99:193-260
31. Rexroad J, Evans RK, Middaugh CR (2006)
Effect of pH and ionic strength on the physical
stability of adenovirus type 5. J Pharm Sci
95(2):237-247
32. Rexroad J, Martin TT, McNeilly D, Godwin S,
Middaugh CR (2006) Thermal stability of
adenovirus type 2 as a function of pH. J Pharm
Sci 95(7):1469-1479
33. Cruz PE, Cunha A, Peixoto CC, Clemente J,
Moreira JL, Carrondo MJ (1998) Optimization
of the production of virus-like particles in insect
cells. Biotechnol Bioeng 60(4):408-418
34. Maranga L, Cunha A, Clemente J, Cruz P,
Carrondo MJ (2004) Scale-up of virus-like
particles production: effects of sparging, agita-
tion and bioreactor scale on cell growth, infec-
tion kinetics and productivity. J Biotechnol
107(1):55-64
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