Application of Lactic Acid Bacteria and Their Bacteriocins for Food Biopreservation - Food Biopreservation - page 18

Table 3.1 Application of b acteriocins in combined treatments
Antimicrobial treatment Reported effects Reference(s)

CO 2 atmosphere Synergism with bacteriocins against foodborne pathogens (nisin,

pediocin PA-1/Ach)

Nilsson et al. 2000 ; Szabo and Cahill 1999

Nitrates, nitrites Enhanced antibacterial activity of nisin in meats against C.

botulinum , Ln. mesenteroides and L. monocytogenes

Rayman et al. 1983 ; Gill and Holley 2003

Organic acids and salts Improve bacteriocin solubility and increase sensitivity of target

bacterial cells in different food substrates (nisin, pediocin PA-1/
AcH, enterocin AS-48, or lacticin 3147…)

Scannell et al. 1997 , 2000 ; Uhart et al. 2004 ; Cobo
Molinos et al. 2005

Sensitize Gram-negative bacteria due to their chelating activity Scannell et al. 1997

Chelating agents
(EDTA,
polyphosphates)

Destabilization of the outer bacterial cell membrane in Gram-
negative bacteria and improving cell permeability to bacteriocins

Stevens et al. 1991 ; Vaara 1992 ; Helander et al. 1997

Sequestration of essential mineral nutrients and indirect
sensitization to bacteriocins on Gram-positive bacteria

Gill and Holley 2000 , 2003

Essential oils and their
bioactive components

Greater inactivation of Gram-positive bacteria and sensitization of
Gram-negative bacteria to bacteriocins

Pol et al. 2001a ; Yuste and Fung 2004 ; Grande et al.
2007 ; Cobo Molinos et al. 2009

Other antimicrobials of
chemical or
proteinaceous nature a

Increased inactivation of Gram-positive and/or Gram-negative
bacteria

Mulet-Powell et al. 1998 ; Gill and Holley 2000 ; Nattress
and Baker 2003 ; Branen and Davidson 2004 ; Boussouel
et al. 2000 ; Naghmouchi et al. 2010 ; Lüders et al. 2003

CO 2 atmosphere Inhibition of strictly aerobic bacteria (complementary action with

bacteriocins)

Economou et al. 2009

Heat Increased inactivation of Gram-positive bacteria Budu-Amoako et al. 1999 ; Ananou et al. 2004

Perturbation of the bacterial outer cell membrane and sensitization
of Gram-negative bacteria to bacteriocins

Kalchayanand et al. 1992 ; Boziaris et al. 1998 ; Ananou
et al. 2005 ; Bakes et al. 2004

Activation of endospore germination and reduced heat resistance
of bacterial endospores

Wandling et al. 1999 ; Grande et al. 2006