Type 1 and 5 secretion systems and associated toxins - Escherichia coli: Pathotypes and Principles of Pathogenesis - page 501

TABLE 16.1 Type 5 secreted proteins of E. coli —cont'd

Pathotypes
predominantly
associated with
the protein

Characterized
virulence
properties

Protein Reference

EhaA EHEC Adhesion to

primary bovine
cell lines. Autoag-
gregation, biofilm
formation

( Wells et al., 2008 )

EhaB/
UpaC

Widespread Biofilm formation,

Adhesion to lam-
inin and collagen I

( Parham et al.,
2004; Wells et al.,
2008 )

EhaD EHEC Bioilm formation ( Wells et al., 2008 )

EhaJ EHEC Biofilm formation,

adhesion to ECM
molecules

( Easton et al., 2011 )

UpaB UPEC Not yet

characterized

( Parham et al.,
2004 )

UpaE UPEC Not yet

characterized

( Parham et al.,
2004 )

UpaH ETEC Bioilm formation ( Allsopp et al., 2010 )

TibA UPEC Adhesion/inva-

sion, autoaggre-
gration, biofilms
formation, self-
recognition

( Lindenthal and
Elsinghorst, 2001;
Sherlock et al.,
2005b )

YcgV Commensal Bioilm formation ( Roux et al., 2005 )

YdeK Commensal Pseudo-gene in

K-12. Not charac-
terized

YejO Commensal Not yet character-

ized

( Roux et al., 2005 )

YfaL/
EhaC

Commensal/
EHEC

YfaL increases
biofilm formation

( Parham et al., 2004;
Roux et al., 2005;
Wells et al., 2008 )

TPS

CdiA,
CdiB

UPEC Contact-dependent

bacterial growth
inhibition

( Aoki et al., 2005 )