Biology Reference
In-Depth Information
Table 7.1 (continued)
Protein class
Examples
Role in Golgi
positioning
Golgi phenotype(when
activity of the regulatory
factor is altered)
References
Actin and associated proteins
Actin
Similar role to kinesin in
opposing dynein
activity
Creates tension by
anchoring at the
plasma membrane to
encourage lateral
spreading of Golgi
membranes
Collapsed Golgi in cell
center
di Campli et al. (
1999
)
Spectrin and ankyrin
Creates flexible
meshwork in close
association with
Golgi membranes
crosslinked by actin
May create membrane
microdomains
necessary to maintain
Golgi morphology
Inhibition in early
anterograde
transport
Godi et al. (
1998
)
Golgi-associated proteins
Hook3
Links microtubules to
Golgi
Fragmented Golgi
Walenta et al. (
2001
)
GMAP210
Not known
Dispersed Golgi mini-stacks
Yadav et al. (
2009
)
Golgin-160
Not known
Dispersed Golgi mini-stacks
Yadav et al. (
2009
)
Golgin-84
Not known
Dispersed Golgi mini-stacks
Diao et al. (
2003
)
Centrosome-associated proteins
TBCCD1
Fragmented Golgi,
mispositioned
centrosome
Goncalves et al. (
2010
)
