Comparative Analysis of Techniques Oriented on the Recognition of Ligand Binding Area in Proteins - Identification of Ligand Binding Site and Protein-Protein Interaction Area - page 65

Fig. 4.4 Comparison of MCC and F-measure results for NAD + -complexing proteins as reported
by ConSurf

comparable results for most other proteins. In approximately 10 cases MCC values
were below 0 (Fig. 4.6 ).

4.5.2 FMN Binding Site Identi fi cation

4.5.2.1 Geometry-Based Packages

The results produced by the CASTp tool for FMN-binding proteins are presented
in Fig. 4.7 . The figure omits cases in which the returned values were below 0.
Three proteins approach 1 on the MCC scale, while F-measure values indicate high
reliability of most of the obtained results (values between 0.2 and 0.5).