clonazepam (Parkinson’s disease)

A muscle relaxant and antispasmodic drug in the benzodiazepine family. it is also used to treat seizures, anxiety, insomnia and pain related to chronic conditions such as fibromyalgia. in Parkinson’s disease clonazepam helps to relieve restless leg syndrome, and dystonia (muscle rigidity). it also is useful in treating the movement disorder myoclonus. As other benzodiazepines are, clonazepam is a central nervous system (CNS) depressant that works by inhibiting the actions of certain neurotransmitters in the brain, most notably gamma-aminobutyric acid (GABA).

There are many potential drug interactions with clonazepam, including with many of the commonly used anti-parkinson’s medications. Clon-azepam may slightly decrease the amount of levodopa that is absorbed into the bloodstream, making it necessary to adjust the levodopa dosage to compensate. The most common undesired side effect is drowsiness, which gradually recedes in most people after two to six weeks of taking the medication as the body adjusts to the drug. This same adjustment process sometimes continues, however, making clonazepam less effective over time. clonazepam is available in the united states in generic forms and as the brand name product Klonopin. Due to clonazepam’s long duration, this drowsiness, as well as other hangover effects such as dizziness, imbalance, confusion, and slowing of thinking, may be big issues in people with Parkinson’s who already have fatigue, balance problems, or cognitive difficulty.

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