Jelly Roll Motif (Molecular Biology)

The jelly roll motif describes a particular topology for arranging eight b-strands into an antiparallel b-sheet that is frequently found in protein structures (Fig. 1). The name comes from the similarity between this b-strand topology and a slice of rolled cake, called a jelly roll or Swiss roll. The jelly roll topology forms a common domain structure in proteins called the jelly roll b-barrel, a type of antiparallel b-barrel.