Chronic Treatments with Hcy-Thiolactone are Harmful As predicted by the Hcy-thiolactone hypothesis [36] [37a, 37b], chronic treatments of animals with Hcy-thiolactone cause pathophysiological changes similar to those observed in human genetic hyperhomocysteinemia. For example, Hcy-thiolactone infusions in baboons [95] or Hcy-thiolactone-supplemented diet in rats [96] produce atherosclerosis. Treatments with Hcy-thiolactone cause developmental abnormalities in chick […]
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