Biomedical Engineering Reference
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Fig. 10.10 Ion-current vs. time traces showing translocation frequency for different salt concentra-
tion ratios between the
cis
and
trans
chambers (
top
). Capture rate as a function of salt concentration
ratio (
bottom
). Reproduced with permission from Wanunu et al. [
50
], Copyright Nature Publishing
Group
large
C
trans
/C
cis
ratios than for symmetric salt conditions [
50
]. Notably, for
C
trans
/C
cis
¼
extends
hundreds of nanometers
away
from the pore before dropping below 50% of its maximum.
20 (4 M/0.2 M KCl),
VðrÞ
10.3 Voltage Driven DNA Translocation
The process of DNA transport through small pores is intriguing both from a
fundamental perspective of investigating polymer behavior in confined volumes,
as well as from a more practical side, which translates the ion current collected
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