Environmental Engineering Reference
In-Depth Information
Important bioactive compounds isolated from this species include lawsaritol,
5α- stigmast-9(11)-en3 β- ol(2), 12-hydroxy-13-methylpodocarpa-9,11,13-trien-3-
one(3), 12-dihydroxy-3,7,11,15-tetramethyl-1,10,14-hexadecatrien-5,13-dione,
and 3,12-dihydroxy-3,7,11,15-tetramethyl-1,6,10,1- hexadeca- tetraen-5,13-dione.
All these compounds have been reported to possess antibacterial activi-
ties against
Pseudomonas aeruginosa
. The alcohol, acetone, and chloroform
extracts of this species showed values of zone of inhibition (mm) of 12, 11, and
8.5, respectively (Patil et al.,
2010).
CH
3
H
3
C
CH
3
CH
3
CH
3
CH
3
HO
lawsaritol
H
3
C
CH
3
H
3
C
CH
3
CH
3
CH
3
O
HO
O
O
5 alpha-stigmast-9(11)-en 3beta-ol
H
S
Me
HO
S
Me
Me
Me
O
12-hydroxy-13-methyl podocarpa-9,11,13-trien-3-one