Environmental Engineering Reference
In-Depth Information
bioactive compounds. All these compounds are responsible for the anti-
pyretic, analgesic, anti-inlammatory and antihelmintic activities of this
species. The polyphenols (tannins) and steroids of this species have shown
antimitotic properties by preventing cell proliferation of pancreatic cancer
cell lines (Patil et al., 2004). This species has also been traditionally used
in the treatment of kidney and bladder stones. Its root tubers have shown
diuretic properties and have been used in the treatment of cough, heart dis-
ease, dysuria (painful urination), blood disorders, fever, poisonings, ulcer,
and uterine diseases (Sivarajan and Balachandran, 1994).
LYSIMACHIA CLETHROIDES
DUBY
Phylum: Magnoliophyta
Class: Magnoliopsida
Order: Primulates
Family: Primulaceae
Common name: Gooseneck loose strife
Distribution: China, Japan, Russia, Korea, North America
Habitat: Damp woodland margins, wet ravines
Description: This perennial, herbaceous, lowering species has a maximum
height of 1 m, and its stem is rigid and upright. The leaves (10 × 5 cm) are
alternate, and oblong or broadly lanceolate with entire margins. The small
white lowers (1 cm wide) with ive petals are grouped in terminal spikes.
Compounds and activities: The oleanane-type triterpenoid saponins, viz. cle-
throidosides A-G and declethroidoside H, have been isolated from this spe-
cies. Of them, declethroidoside H has been found to be cytotoxic against
human tumor cell lines (HT-29, He PG 2, BGC-823, A 549, A 375 S180,
H22 U14, and L1210) (Liang et al., 2011). The plant extract also reduces cell
apoptosis in HL-60, SMMC-7721, and K562 cells, and inhibited metastasis
in hepatoma and uterine cervix cancer (Yang et al.,
2009).
