Environmental Engineering Reference
In-Depth Information
Common name: Yellow pond lily
Distribution: Europe, Northwest Africa, Western Asia
Habitat: Shallow waters, wetlands, ponds, slow streams
Description: This species, rooted in sediments, grows in water up to 5 m deep.
Its leaves loat on the water surface. The solitary terminal and hermaphro-
ditic lower (3-5 cm diameter), which has many yellow petals, is also held
above the water surface.
Compounds and activities: The bioactive compounds isolated from this
species include thionupharidines, thionuphlutidines, nupharolutine, and
6,6-dihydroxythiobinupharidine. Other compounds of this species are
nuphor alkaloids (NUPs) and dimeric sesquiterpene thioalkaloids contain-
ing thionupharidines. The NUPs inhibit the NF kappa B pathway and serve
as sensitizers to conventional chemotherapy, which may have applications
against cancer and inlammation (Ozer et al., 2009). The dimeric sesquiter-
pene thioalkaloids, however, have shown antibacterial and antileishmanial
(against the protozoan parasite, Leishmania major ) activities. This plant is
also used in homeopathic medicines.
CH 3
H
O
O
N
HO
H
H 3 C
N
S
Cl
O
thionupharidines
nupharolutine
O
O
HO
OH
S
S
S
N
N
S
R
S
S
S
S
R
R
H
H
Me
Me
6,6-dihydroxythiobinupharidine
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