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Areca
Nenga
Pinanga
Gronop yllum ,
Gul bia ,
Hydristele ,
Sipho entia
Arecinae
Subtribe
Loxococus
Figure 6.1 Phylogeny of Arecinae subtribe.
concina
• triandra
catechu
Areca
Nenga
Pinanga
Figure 6.2 Phylogeny of areca clade of Arecinae subtribe.
6.3 Arecanut and Health Hazards
Arecanut, also called betel nut palm, is known as a mild stimulant and used by
200-400 million people [7] along with betel leaf ( Piper betle ), lime, and some-
times tobacco and spices. Arecanut is the fourth most ( Figure 6.3 ) abused sub-
stance in the world [8] , after nicotine (tobacco), alcohol, and caffeine, as well as a
main cause of oral cancers. Arecanut-associated oral cancer or oral squamous cell
carcinoma (OSCC) is the third most common malignancy in developing countries.
Frequent consumption of areca causes a general fibrotic change in the cavity of oral
submucosa and oral submucous fibrosis (OSF). It also leads to rigidity of oral and
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