Biomedical Engineering Reference
In-Depth Information
Figure 5 (A) Shows a photomicrograph of the epithelium where a liquid layer can
be seen lining the airway surface in a guinea pig lung that has been expose to cigar-
ette smoke. Inflammatory cells can be seen migrating to the surface between the
epithelial cells (arrows). (B) Shows a diseased small airway in cross-section where
one microvascular bed can be seen beneath the reticular basement membrane (single
arrow) and a second in the adventitial space outside the muscle layer (double arrow).
These two microvascular beds are connected by vessels that penetrate the muscle
layer (arrow head). (C) Shows a diagram of a regional lymph node where the afferent
vessel can be seen penetrating the capsule and the efferent vessel leaves at the hilum
of the node. The lymphoid follicles are supplied by a cuff of vessels that allow the
lymphocytes to migrate out of high endothelial venules into the lymphoid tissue.
(See text foe further explanation). (D) Shows a collection of bronchial associated
lymphoid tissue (BALT) with a surface covering of M-cells and underlying lymphoid
follicle that has an active germinal center.
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