Biomedical Engineering Reference
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53. Bartmann K, Fooke-Achterrath M, Koch G, Nagy I, Schutz I, Weis E, Zierski
M. Heterozygosity in the Pi-system as a pathogenetic cofactor in chronic
obstructive pulmonary disease (COPD). Eur J Respir Dis 1985; 66:284-296.
54. Janus ED. a 1 -Antitrypsin Pi types in COPD patients. Chest 1988; 94:446-447.
55. Lieberman J, Winter B, Sastre A. a 1 -Antitrypsin Pi-types in 965 COPD
patients. Chest 1986; 89:370-373.
56. Sandford AJ, Weir TD, Spinelli JJ, Par ´ PD. Z and S mutations of the
a 1 -antitrypsin gene and the risk of chronic obstructive pulmonary disease.
Am J Respir Cell Mol Biol 1999; 20:287-291.
57. Sandford AJ, Weir TD, Par´ PD. Genetic risk factors for chronic obstructive
pulmonary disease. Eur Respir J 1997; 10:1380-1391.
58. Sandford AJ, Chagani T, Weir TD, Connett JE, Anthonisen NR, Par´ PD.
Susceptibility genes for rapid decline of lung function in the Lung Health
Study. Am J Respir Crit Care Med 2001; 163:469-473.
59. Chan-Yeung M, Ashley MJ, Corey P, Maledy H. Pi phenotypes and the
prevalence of chest symptoms and lung function abnormalities in workers
employed in dusty industries. Am Rev Respir Dis 1978; 117:239-245.
60. McDonagh DJ, Nathan SP, Knudson RJ, Lebowitz MD. Assessment of
alpha 1 -antitrypsin deficiency heterozygosity as a risk factor in the etiology
of emphysema. Physiological comparison of adult nonnal and heterozygous
protease inhibitor phenotype subjects from a random population. J Clin
Invest 1979; 63:299-309.
61. Buist AS, Sexton GJ, Azzam AM, Adams BE. Pulmonary function in hetero-
zygotes for a 1 -antitrypsin deficiency: a case-control study. Am Rev Respir Dis
1979; 120:759-766.
62. Bruce RM, Cohen BH, Diamond EL, Fallat RJ, Knudson RJ, Lebowitz MD,
Mittman C, Patterson CD, Tockman MS. Collaborative study to assess risk
of lung disease in Pi MZ phenotype subjects. Am Rev Respir Dis 1984; 130:
386-390.
63. Seersholm N, Wilcke JT, Kok-Jensen A, Dirksen A. Risk of hospital admis-
sion for obstructive pulmonary disease in alpha(l)-antitrypsin heterozygotes
of phenotype PiMZ. Am J Respir Crit Care Med 2000; 161:81-84.
64. Dahl M, Nordestgaard BG, Lange P, Vestbo J, Tybjaerg-Hansen A. Molecu-
lar diagnosis of intermediate and severe alpha(l)-antitrypsin deficiency: MZ
individuals with chronic obstructive pulmonary disease may have lower lung
function than MM individuals. Clin Chem 2001; 47:56-62.
65. Dahl M, Tybjaerg-Hansen A, Lange P, Vestbo J, Nordestgaard BG. Change
in lung function and morbidity from chronic obstructive pulmonary disease in
alpha l -antitrypsin MZ heterozygotes: a longitudinal study of the general
population. Ann Intern Med 2002; 136:270-279.
66. Kalsheker NA, Watkins GL, Hill S, Morgan K, Stockley RA, Fick RB. Inde-
pendent mutations in the flanking sequence of the a 1 -antitrypsin gene are asso-
ciated with chronic obstructive airways disease. Dis Markers 1990; 8:151-157.
67. Poller W, Meisen C, Olek K. DNA polymorphisms of the a 1 -antitrypsin gene
region in patients with chronic obstructive pulmonary disease. Eur J Clin
Invest 1990; 20:1-7.
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