Biomedical Engineering Reference
In-Depth Information
cells in airways in chronic obstructive pulmonary disease. Am J Respir Crit
Care Med 1998; 158:1951-1957.
52. Takeyama K, Jung B, Shim JJ, Burgel PR, Dao-Pick T, Ueki IF, et al. Activa-
tion of epidermal growth factor receptors is responsible for mucin synthesis
induced by cigarette smoke. Am J Physiol Lung Cell Mol Physiol 2001;
280:L165-L172.
53. Macnee W. Oxidants
=
antioxidants and COPD. Chest 2000; 117:303S-317S.
54. Iles KE, Forman HJ. Macrophage signaling and respiratory burst. Immunol
Res 2002; 26:95-105.
55. Weinberg JB. Nitric oxide production and nitric oxide synthase type 2 expres-
sion by human mononuclear phagocytes: a review. Mol Med 1998; 4:557-591.
56. Ichinose M, Sugiura H, Yamagata S, Koarai A, Shirato K. Increase in reactive
nitrogen species production in chronic obstructive pulmonary disease airways.
Am J Resp Crit Care Med 2000; 160:701-706.
57. van Straaten JF, Postma DS, Coers W, Noordhoek JA, Kauffman HF, Timens
W. Macrophages in lung tissue from patients with pulmonary emphysema
express both inducible and endothelial nitric oxide synthase. Mod Pathol
1998; 11:648-655.
58. Maestrelli P, Paska A, Saetta M, Turato G, Nowicki Y, Monti S, et al.
Decreased haem oxygenase-1 and increased inducible nitric oxide synthase in
the lung of severe COPD patients. Eur Respir J 2003; 21:971-976.
59. Di Stefano A, Caramori G, Capelli A, Lusuardi M, Gnemmi I, Ioli F, et al.
Increased expression of NF-
k
B in bronchial biopsies from smokers and patients
with COPD. Eur Resp J 2002; 20:556-563.
60. Caramori G, Romagnoli M, Casolari P, Bellettato C, Casoni G, Boschetto P,
et al. Nuclear localisation of p65 in sputum macrophages but not in sputum
neutrophils during COPD exacerbations. Thorax 2003; 58:348-351.
61. Koch A, Giembycz M, Ito K, Lim S, Jazrawi E, Barnes PJ, et al. MAP-kinase
modulation of NF-
k
B-induced GM-CSF release from human alveolar macro-
phages. Am J Respir Cell Mol Biol 2004; 30:342-349.
62. Carter AB, Monick MM, Hunninghake GW. Both ERK and p38 kinases are
necessary for cytokine gene transcription. Am J Respir Cell Mol Biol 1999;
20:751-758.
63. Urnov FD, Wolffe AP. Chromatin remodeling and transcriptional activation:
the cast (in order of appearance). Oncogene 2001; 20:2991-3006.
64. Ito K, Barnes PJ, Adcock IM. Glucocorticoid receptor recruitment of histone
deacetylase 2 inhibits IL-1
b
-induced histone H4 acetylation on lysines 8 and 12.
Mol Cell Biol 2000; 20:6891-6903.
65. Ito K, Lim S, Caramori G, Chung KF, Barnes PJ, Adcock IM. Cigarette smok-
ing reduces histone deacetylase 2 expression, enhances cytokine expression and
inhibits glucocorticoid actions in alveolar macrophages. FASEB J 2001;
15:1100-1102.
66. Punturieri A, Filippov S, Allen E, Caras I, Murray R, Reddy V, et al. Regula-
tion of elastinolytic cysteine proteinase activity in normal and cathepsin K-
deficient human macrophages. J Exp Med 2000; 192:789-800.
67. Russell RE, Thorley A, Culpitt SV, Dodd S, Donnelly LE, Demattos C, et al.
Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases,
