UV RADIATION, DNA DAMAGE, MUTATIONS AND SKIN CANCER - Environmental UV Radiation: Impact on Ecosystems and Human Health and Predictive Models - page 248

28. Jonason AS, Kunala S, Price GJ, Restifo RJ, Spinelli HM, Persing JA, Leffell DJ, Tarone RE. and Brash
DE. Frequent clones of p53 -mutated keratinocytes in normal human skin, Proc. Natl. Acad. Sci. USA , 93:
(1996) 14025-14029.
29. Ren ZP, Ponten F, Nister M. and Ponten J. Two distinct p53 immunohistochemical patterns in human
squamous cell skin cancer, precursors and normal epidermis, Int. J. Cancer , 69: (1996) 174-179.
30. Rebel H, Mosnier LO, Berg RJ, Westerman-de Vries A, van Steeg H, van Kranen HJ. and de Gruijl FR.
Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of
induction, effects of DNA repair deficiency, and p53 heterozygozity, Cancer Res. , 61: (2001) 977-983.
31. Pierceall WE, Goldberg LH, Tainsky MA, Mukhopadhyay T. and Ananthaswamy HN. Ras gene mutation
and amplification in human nonmelanoma skin cancers, Mol. Carcinog. , 4: (1991) 196-202.
32. Cambell C, Quinn AG. and Rees JL. Codon 12 Harvey-ras mutations are rare events in non-melanoma
human skin cancer, Br. J. Dermatol. , 128: (1993) 111-114.
33.Hahn H, Wicking C, Zaphiropoulos PG, Gailini MR, Shanley S, Chidambaram A, Vorechovsky I,
Holmberg E, Unden AB, Gilles S, Nagus K, Smyth I, Pressman C, Leffell DJ, Gerrard B, Goldstein AM,
Dean M, Toftgard R, Chenerix-Trench G, Wainright B. and Bale AE. Mutations of the human homologue
of Drosophila Patches in the Nevoid Basal Cell Carcinoma Syndrome, Cell , 85: (1996) 841-851.
34. Gailini MR, Stahle-Bäckdahl M, Leffell DJ, Glynn M, Zaphiropoulos PG, Pressman C, Unden AB, Dean
M, Brash DE, Bale AE. and Toftgard R. The role of the human homologue of Drosophila Patched in
sporadic basal cell carcinomas, Nature Gen. , 14: (1996) 78-81.
35. Fan H. and Khavari PA. Sonic hedgehog opposes epithelial cell cycle arrest, J. Cell Biol. , 147: (1999) 71-
76.
36. Dahmane N, Lee J, Robins P, Heller P. and Ruiz i Altaba A, Activation of the transcription factor Gli1 and
the Sonic Hedgehog signalling pathway in skin tumours, Nature , 389: (1997) 876-881.
37. Fan H, Oro AE, Scott MP and Khavari PA, Induction of basal cell carcinoma features in transgenic human
skin expressing Sonic Hedgehog, Nature Med. , 3: (1997) 788-92.
38. Goodrich LV, Millenkovic L, Higgins KM. and Scott MP. Altered neural cell fates and medullablastomas
in mouse patched mutants, Science , 277: (1997) 1109-1113.
39. Hahn H, Wojnowski L, Zimmer AM, Hall J, Miller G. and Zimmer A. Rhabdomyosarcomas and radiation
hypersensitivity in a mouse model of Gorlin syndrome, Nature Med. , 4: (1998) 619-622.
40. Aszterbaum M, Epstein J, Oro A, Douglas V, LeBoit PE, Scott MP. and Epstein EH Jr. Ultraviolet and
ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout
mice, Nature Med. , 5: (1999) 1285-1291.
41. Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, Stockert E, Day RS III,
Johnson BE. and Skolnick MH. A cell cycle regulator potentially involved in geneisis of many tumor
types, Science , 264: (1994) 436-440.
42. Ruas, M.. and Peters G. The p16 INK4a /CDKN2A tumor suppressor and its relatives, Biochim. Biophys.
Acta , 1378: (1998) F115-F177.
43. Zhang H, Xiong Y. and Yarbrough WG. ARF promotes MDM2 degradation and stabalizes p53: ARF-
INK4a locus deletion impairs both Rb and p53 tumor suppressor pathways, Cell , 92: (1998) 725-734.
44.Pollock PM, Yu F, Qui L, Parsons PG. and Hayward NK. Evidence for u.v. induction of CDKN2
mutations in melanoma cell lines, Oncogene , 11: (1995) 663-668.
45. Lee JY, Dong SM, Shin MS, Kim SY, Lee SH, Kang SJ, Lee JD, Kim CS, Kim SH. and Yoo NJ. Genetic
alterations of p16INK4a and p53 genes in sporadic dysplastic nevus, Biochem. Biophys. Res. Comm ., 237:
(1997) 667-672.
46. Van Elsas A, Zerp SF, van der Flier S, Kruse KM, Aarnoudse C, Hayward NK, Ruiter DJ. and Schrier PI.
Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human
cutaneous melanoma, Am. J. Path. , 143: (1996) 883-893.
47. Van 't Veer LJ, Burgering BMT, Versteeg R, Boot AJM, Ruiter DJ, Osanto S, Schrier PI. and Bos JL. N-
ras mutations in human cutaneous melanoma from sun-exposed body sites, Mol. Cell. Biol ., :(1989) 3114-
3116.
48. Serrano M, Lin WA, McCurrach ME, Beach D. and Lowe SW. Oncogenic ras provokes premature cell
senescence associated with accumulation of p53 and p16 INK4a , Cell , 88: (1997) 593-602.
49. Sharpless NE. and DePinho RA. The INK4A/ARF locus and its two gene products, Curr. Opin. Genes
Dev ., 9: (1999) 22-30.
50. Wittbrodt J, Adam D, Malitschek B, Mäueler W, Raulf F, Telling A, Robertson SM. and Schartl M. Novel
putative receptor tyrosine kinase encoded by melanoma-inducing Tu locus in Xiphophorus , Nature , 341:
(1989) 415-421.