Biology Reference
In-Depth Information
Defects
Test
Mouse
Rat
Dog
Cat
Rabbit
Pig
NHP
Personality changes/
emotional disorders/
behavioral disorders
Elevated-plus maze
Open-fi eld test
Light-dark
exploration test
Social interaction test
Shock probe defensive
burying test
Novelty-induced
hypophagia
(
114, 183
)
(
97, 114
)
(
114, 187
)
(
159, 181, 182
)
(
52, 171
)
(
185, 186
)
(
116
)
(
96, 116
)
(
116
)
(
175, 176
) (
178, 179
) (
172, 173
)
(
180
)
(
114, 190
)
(
195, 196
)
(
159, 188
)
(
159, 193
)
(
114, 199
)
(
197, 198
)
Attentional set shifting
See above in attention defi cits
Affect lability, disinhibi-
tion, and/or syn-
drome (depression)
Organic personality
disorder
Forced swimming test
Tail suspension test
(
201, 203
)
(
201, 204
)
(
201, 202
)
No appropriate tests
available
Apathy and loss
of interest
No appropriate tests
available
Impairment of social
judgment
No appropriate tests
available
Aggressiveness or rage
Social interaction test
See above in personality changes/emotional disorders/behavioral disorders
Organic psychosocial
maladjustment
No appropriate tests available
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