Biology Reference
In-Depth Information
Table 1
SAH/vasospasm models in vivo
Animal/route
Mouse
Rat
Rabbit
Cat
Dog
Pig
Primate
Local
+
+
Endovascular
+
+
+
-
+
Craniotomy
+
+
+
+
+
Intrathecal
+
+ (single or double
injection)
+
+
+ (single or double
injection)
+
+
The chapters that follow are focused on continued efforts to
conquer these challenges and reveal the true nature of vasospasm
after aSAH. In the pursuit of this goal, they address experimental
and clinical methods of vasospasm assessment, its effects, and imag-
ing in the context of vasospasm research.
Acknowledgement
This research was partially supported by the Intramural Research
Program of the NIH, NINDS.
References
1. Ljunggren B et al (1981) Results of early oper-
ations for ruptured aneurysms. J Neurosurg
54(4):473-9
2. Schievink W (1997) Intracranial aneurysms.
NEJM 336:28-40
3. Burnett M et al (2004) Pathology and
pathophysiology of aneurysmal subarachnoid
hemorrhage. In: Leroux P, Winn W, Newell D
(eds) Management of cerebral aneurysms.
Elsevier Inc., Philadelphia, PA, pp 127-137
4. Zucker M (1944) A study of the substances in
blood serum and platelets which stimulate
smooth muscle. Am J Physiol 142:12-26
5. Fisher C, Kistler J, Davis K (1980) Relation of
cerebral vasospasm to subarachnoid hemor-
rhage visualized by computerized tomographic
scanning. Neurosurgery 6:1-6
6. Macdonald R, Weir B (1991) A review of
hemoglobin and the pathogenesis of cerebral
vasospasm. Stroke 22:971-982
7. Ecker A, Rimenschneider P (1951) Arteriographic
demonstration of spasm of the intracranial arteries
with special reference to saccular arterial aneu-
rysms. J Neurosurg 8:660-667
8. Weir B et al (1978) Time course of vasospasm
in man. J Neurosurg 48:173-178
9. Johnston SC, Selvin S, Gress DR (1998) The
burden, trends, and demographics of mortality
from subarachnoid hemorrhage. Neurology
50(5):1413-8
10. Gotoh O et al. (1991) The incidence of vasos-
pasm following acute aneurysm surgery. In:
Proceedings of 59th Annual Meeting of
American Association of Neurological Surgeons.
New Orleans, LA.
11. Bloor BM, Glista GG (1977) Observations on
simultaneous internal carotid artery and total
cerebral blood fl ow measurements in man.
Neurosurgery 1(3):249-55
12. Macdonald RL, Pluta RM, Zhang JH (2007)
Cerebral vasospasm after subarachnoid hemor-
rhage: the emerging revolution. Nat Clin Pract
Neurol 3(5):256-63
13. Pluta RM et al (2009) Cerebral vasospasm fol-
lowing subarachnoid hemorrhage: time for a new
world of thought. Neurol Res 31(2):151-8
14. Macdonald RL et al (2008) Clazosentan to
overcome neurological ischemia and infarction
Search WWH ::
Custom Search