Neurobehavioral Assessments of Subarachnoid Hemorrhage - Animal Models of Acute Neurological Injuries: Injury and Mechanistic Assessments - page 417

Table 1
Modifi ed Garcia's score

0 1 2 3

Spontaneous
activity

Not approach
any wall
of cage

Approach one
wall of cage

Approach two
walls of cage

Approach at least
three walls of
cage

Spontaneous move-
ment of all four
limbs

No movement Limited

movement

Move fully
but slowly

Move the same as
pre-SAH

Forepaw
outstretching

No
outstretching

Slight
outstretching

Limited
outstretching

Outstretch
the same as
pre-SAH

Climbing Fall from slope Failed climbing Weak climbing Normal climbing

Body
proprioception

- No response Weak response Normal response

Response to
vibrissae touch

- No response Weak response Normal response

3.2. Spontaneous
Movement of
All Four Limbs

1. Hold an animal in the air by the tail.
2. Observe the movement of the four limbs.
3. Scores indicate the following:
3, all four limbs extend symmetrically and move the same as
presurgery.
2, all four limbs extend more slowly compared with presurgery.
1, at least one limb shows limited movement.
0, at least one limb shows no movement.

3.3. Forepaw
Outstretching

1. Bring up an animal to the edge of the table and make it to walk
on forelimbs while being held by the tail.
2. Observe the outstretching of both forelimbs while the animal
reaches the table and the hindlimbs are kept in the air.
3. Scores indicate the following:
3, both forelimbs are outstretched, and the animal walks on
forepaws the same as presurgery.
2, one or both forelimbs are outstretched less than presurgery
and forepaw walking is impaired.
1, one or both forelimbs move minimally.
0, one or both forelimbs do not move.