Biomedical Engineering Reference
In-Depth Information
Nanoparticles Enhanced Hyperthermia
Qian Wang and Jing Liu
Abstract Nano-hyperthermia is regarded as a promising alternative to conventional
thermal ablation. Many nanoparticles with specific physical properties in electrical,
magnetic, acoustic, optical or thermal features have been tried to induce various
enhanced hyperthermia, aiming to significantly improve the treatment efficiency
of conventional heating. This article is dedicated to present a comprehensive review
on the thermal properties, targeted heating mechanisms, and heat generation beha-
viors of typical nanoparticles. In addition, potential combination of the nanoparticles
with radiotherapy and/or chemotherapy will also be discussed.
Keywords Hyperthermia • Nanoparticle • Nanomedicine • Thermal ablation
• Physical therapy
Abbreviations
CNT
Carbon nanotube
CVD
Chemical vapor deposition
GNP
Gold nanoparticle
HF
High frequency
HIFU
High intensity focused ultrasound
LF
Low frequency
LITT
Laser-induced thermotherapy
MF
Middle frequency
MGC
Magnetic glass-ceramic
MNP
Magnetic nanoparticle
MRI
Magnetic resonance imaging
Q. Wang and J. Liu ( * )
Department of Biomedical Engineering, School of Medicine,
Tsinghua University, Beijing 100084, P. R. China
e-mail: jliubme@tsinghua.edu.cn
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