Biomedical Engineering Reference
In-Depth Information
Name
Targeting agent
Therapeutic agent
Status
Nanovector
References
MBP-426
Transferrin
Oxaliplatin
Phase I
Liposome nanoparticle
containing human
transferrin protein
targeting agent
Phan (
2007
)
Clinicaltrials.gov -
NCT00470613 (
2008
)
SGT-53
Antibody fragment
to transferrin
receptor
Plasmid DNA with
p53 gene
Phase I
Liposome nanoparticle
containing antibody
fragment targeting
agent
CALAA-01
Transferrin
Small interfering RNA
Phase I
Polymer-based nanoparticle
containing human
transferrin protein
targeting agent
Davis et al. (
2010
)
111
In-DTPA-folate
Folic acid
111
In-diethylenetriamine-
pentaacetic
acid
Phase I/II
Radiopharmaceutical
Siegel et al. (
2003
)
99m
Tc-EC-20
Folic acid
Phase I/II
Radiopharm.
Fisher et al. (
2008
)
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