Biosynthesis of Metallic Nanoparticles and Their Applications - Intracellular Delivery: Fundamentals and Applications - page 399

Although research in the field has been dramatically increasing since the beginning
of the decade, biofabrication methods and approaches are still on the horizon of
genuine applied research. This rapidly spreading, interdisciplinary field will require
great research efforts from biochemists, physicists, biologists and materials scien-
tists. A greater understanding of particular application mechanisms (how such tech-
nology will be utilized in the real world) will lead to mark crucial assets and
drawbacks of bio-methods. In order to fully exploit biosynthesized metallic NPs,
better stabilization techniques, more efficient material definition, better isolation
processes and more effective immobilization possibilities should be designed and
developed. To address these issues, the novel methods (organisms, substrates) should
be incorporated and stabilization and capping mechanisms must be further investi-
gated. Last but not least, possibilities of varied biosynthesized shapes (e.g. disk, plate,
sponge, star, flake, urchin, prisms, wires and rods) are also quite promising.
Based on this study, we anticipate further development of biosynthesis methods
and their utilization in many pertinent and advantageous real-world applications. In
combination with other NP preparation methods, further investigation of processes
and an expansion of potential applications will result in the deeper development of
bionanotechnology.
Acknowledgments This work was supported by Ministry of Education, Youth and Sports of
Czech Republic (research grant MSM 6198910016).
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