Biomedical Engineering Reference
In-Depth Information
Magnetic Nanoparticles for Biomedicine
Ivo Šafařík, Kateřina Horská, and Mirka Šafaříková
Abstract Biocompatible materials exhibiting different types of response to external
magnetic field have already found many important applications in various areas of
biosciences, biotechnology, medicine, environmental technology etc. In most cases
they can be described as composite materials, where the magnetic properties are
caused by the presence of iron oxides nano- or microparticles. Such materials can
be efficiently separated from difficult-to-handle samples and targeted to the desired
place, applied as contrast agents for magnetic resonance imaging or used to generate
heat during exposure to alternating magnetic field.
Keywords Maghemite Magnetic iron oxides Magnetic particles Magnetic
separation Magnetite
1
Introduction
Biocompatible materials exhibiting response to external magnetic field have
found many interesting applications in various areas of biosciences and biotech-
nology, including different medical disciplines. The broad family of magnetic
field-controllable materials includes both nano- and microparticles, high aspect
ratio structures (nanotubes, nanowires), thin films, etc. Ferrofluids (magnetic
I. Šafařík ( )
Department of Nanobiotechnology, Institute of Nanobiology and Structural Biology of GCRC,
Academy of Sciences of the Czech Republic, Na Sádkách 7, 370 05 České Budějovice,
Czech Republic
and
Regional Centre of Advanced Technologies and Materials, Palacký University, Šlechtitelů 11,
783 71, Olomouc, Czech Republic
e-mail: ivosaf@yahoo.com
K. Horská and M. Šafaříková
Department of Nanobiotechnology, Institute of Nanobiology and Structural Biology of GCRC,
Academy of Sciences of the Czech Republic, Na Sádkách 7, 370 05 České Budějovice,
Czech Republic
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