Biomedical Engineering Reference
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Fig. 13 Self assembly of ( a ) RGD4C-PEO-P(CL-Hyd-DOX) and ( b ) RGD4C-PEO-P(CL-Ami-
DOX) copolymers into targeted micelles. ( c ) Endosome, mitochondrial versus nuclear distribution
of DOX as part of ( a ) RGD4C-PEO-P(CL-Ami-DOX) and ( b ) RGD4C-PEO-P(CL-Hyd-DOX)
micelles in MDA-435/LCC6 WT and MDA-435/LCC6 MDR cells. Cells were incubated with
( a ) RGD4C-PEO-P(CL-Ami-DOX) micelles and ( b ) RGD4C-PEO-P(CL-Hyd-DOX) micelles
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