Simulation Based Analysis of Nanocarrier Internalization: Exciting Challenges with a New Computational Tool - Intracellular Delivery: Fundamentals and Applications - page 142

Table 2 State elements and initial concentrations

ext
(External)

pm (Plasma
membrane)

cyt
(Cytosol)

ee (Early
endosome)

le (Late
endosome)

lys
(Lysosome)

mit
(mitochondrial)

nuc
(nucleus) Compartment

Reference
measures of
compartments 5 0.005 5.4 0.01 0.01 0.01 2.2 0.6

Components,
SU

NV 0 0 0

NV_L 0 0 0

D 0 0

NV_L_D 0.3 0 0 0 0 0

NV_D 0 0 0

R 10

NV_L_D_R 0 0 0

Degr 0

Targ 0.2

Targ_D 0

Mot 0 0.3

Mot_NV_L 0 0

Mot_NV 0 0

Mot_NV_D 5 0

Lip 0

Lip_NV_L_D 0