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Table 10.1 Detection of Inflammatory Mediator Production and Function in Rodents and
Humans Following Traumatic Brain Injury
Experimental Approach
IL-1
TNF
IL-6
[ 139 ]
Human CSF/serum/microdialysate
[101]
[79]
[102]
[80]
[49,53]
[103]
[81]
[55]
[ 140 ]
[104]
[55]
[105]
[59]
[ 141 ]
[109]
[106]
[104]
[107]
[60]
[108]
[62]
[105]
[61]
[106]
[108]
[ 142 ]
Rodent brain/microdialysate
[68]
[68]
[ 143 ]
[68]
[64]
[64]
[63]
[64]
[93]
[76]
[63]
[66]
[78]
[66]
[94]
[77]
[57]
[95]
[65]
[65]
[67]
[90]
[67]
[82]
[82]
[69]
[69]
[83]
[83]
Application of binding protein/soluble
receptors or receptor-antagonists,
antibodies
[142]
[85]
[87]
[96]
[77]
[97]
[87]
[95]
Anti-inflammatory agents: pentoxifylline,
dexabinol (NMDA antagonist), IL-1ra,
ICE-inhibitor, IL-10, minocycline, EPO,
hypothermia
[96]
[85,86]
[86]
[ 144 ]
[97]
[17]
[ 145 ]
[94]
( Continued )
 
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