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and developed by integrating designs based on the structural features of ABA
analogues and the biochemical activity of CYP707A (Araki et al. 2006 ; Ueno
et al. 2005 ). AHI4 does not exhibit ABA activity such as growth arrest and germi-
nation inhibition, but it strongly inhibits the activity of ABA 8′-hydroxylase (Araki
et al. 2006 ). Therefore, co-treatment of ABA and AHI4 enhances ABA's activ-
ity, and application of AHI4 confers drought stress tolerance (Araki et al. 2006 ).
Specific inhibitors are useful not only for understanding ABA metabolic regula-
tion, but also as agrochemicals that can control the action of ABA in crops.
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