Agriculture Reference
In-Depth Information
Chapter 9
Protein Ubiquitination and Sumoylation
in ABA Signaling
Yaorong Wu, Feifei Yu and Qi Xie
Abstract Abscisic acid (ABA) has been known as a key phytohormone to reg-
ulate plant and environmental interaction to modulate plant growth and devel-
opment under different environmental diversification. ABA signaling could
be regulated at different levels, most importantly at transcriptional and post-
translational levels. Among them, ubiquitination and sumoylation have been
paid attention especially in recent years. Ubiquitination and sumoylation share
similar biochemistry pathways, but a three-step enzymatic cascade catalyzed by
their specific E1, E2, and E3 enzymes, respectively. Both kinds of post-transla-
tional protein modifications can act together or separately to control protein sta-
bility, localization, and activity. In this chapter, we will summarize the recent
development of protein ubiquitination and sumoylation in control of ABA path-
way, including ABA biogenesis and signaling, mainly based on the data from
researches in the model plant Arabidopsis.
Keywords Ubiquitination · Sumoylation · ABA signaling
9.1 Introduction
Ubiquitin and small ubiquitin-like modifier (SUMO) are small proteins that can
regulate the stability, localization, or function of the target proteins in eukary-
otic systems by being covalently attached to substrate proteins. Ubiquitination
and sumoylation involve a three-step enzymatic cascade catalyzed by their spe-
cific E1, E2, and E3 enzymes, respectively. In many aspects, ubiquitination and
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