Biology Reference
In-Depth Information
Table 12.3 The frequency distributions of the eight modules or mechanisms of RNA metabolism
as the functions of the five time periods following the glucose-galactose shift. If the angles
are homogeneously distributed over 360 ,
the expected distributions can be calculated as
(6/360)
23.3% for
Mechanisms 2, 4, 6, and 8 (see the seventh row). The p-values for the difference between the
observed and the expected distributions are given in the last row. The differences are all signifi-
cant, except for Mechanism or Module 5 (Reproduced from Ji et al. 2009a)
Mechanism
segments
100
¼
1.67% for Mechanisms 1, 3, 4, and 7 and (84/360)
100
¼
1
2
3
4
5
6
7
8
Total
1
0
142
234
3,470
96
1,732
12
39
5,725
2
14
18
3
37
5
3,729
617
1,302
5,725
3
340
1,914
52
638
314
1,471
28
968
5,725
4
477
4,237
21
151
61
143
19
616
5,725
5
12
1,151
238
4,213
38
56
4
13
5,725
Total, observed
843
7,462
548
8,509
514
7,131
680
2,938
28,625
(%)
(2.94)
(26.07)
(1.91)
(29.73)
(1.80)
(24.91)
(2.38)
(10.26)
Total, expected
477
6,678
477
6,678
477
6,678
477
6,678
28,625
(%)
(1.67)
(23.33)
(1.67)
(23.33)
(1.67)
(23.33)
(1.67)
(23.33)
p-value
0
0
0.0011 0
0.0919 0.0000 0
0
FREQUENCY
8000
7000
6000
5000
4000
3000
2000
1000
0
0123456789
mech MIDPOINT
Fig. 12.9 The frequency distributions of the RNA metabolic modules in budding yeast undergoing
the glucose-galactose shift. This histogram is a visual representation of the data shown in Table 12.3 .
The y -axis records the frequency of the occurrence of individual modules defined by the ranges of
the angles of the component segments/vectors of the TL-TR trajectories in Fig. 12.6 and the x -axis
lists the nine mechanisms or modules of RNA metabolism (Reproduced from Ji et al. 2009a)
Search WWH ::




Custom Search