Biology Reference
In-Depth Information
Fig. 12.1 Typical examples of the time-dependent RNA levels measured in budding yeast with
DNA microarrays after switching glucose to galactose in the growth medium at t
ΒΌ
0 (Garcia-
Martinez et al. 2004). Each data point is the average of three measurements. Panels a, b, and c
show the RNA level trajectories of 15 genes chosen randomly out of over 6,000 genes in three
different ranges on the
y
-axes, namely, between 0 and 60 RNA molecules per cell in Panel a,
between 0 and 10 in Panel b, and between 0 and 1 in Panel c. Panel d depicts the average kinetics
of the RNA molecules encoded by 5,836 genes. See Ji et al. (2009a) for the details involved in
calibrating microarray signals in absolute units of RNA molecules per cell. A similar set of graphs
are shown in Fig.
9.1
