Biology Reference
In-Depth Information
Table 4.6 Blackbody radiation law-like equation (BRE) is obeyed by (1) blackbody radiation, (2) single-molecule enzymic activity of cholesterol oxidase,
(3) whole-cell RNA metabolism in budding yeast, and (4) protein stability data (see Sects.
11.3.3
and
12.12
for more details)
y
a(Ax + B )
5
/(e
b/(Ax + B)
ΒΌ
1)
Process
a
b
A
B
a/b
y
x
10
15
10
13
10
2
1. Blackbody
radiation
5
4.8
1
0
1.04
Spectral intensity
Wavelength
10
5
10
2
10
3
Waiting time
a
2. Single-molecule
enzymic catalysis
3.5
2.0
1
0
1.75
Frequency of occurrences
10
8
10
7
Phenotypic similarity classes
c
3. Distances between
RNA pairs in the
concentration
space; catalysis by
enzyme complexes
b
8.8
50
2.23
3.21
1.7
Frequency of occurrences
1.8
10
10
6.0
10
7
4. Protein stability/
unfolding
300
14
18
Frequency of the occurrence
of
D
G
D
G, i.e., the Gibbs free energy
of the native conformation
of a protein
a
The time an enzyme waits until it begins its next cycle of catalysis. The longer the waiting time, the slower the catalytic rate constant. See Rows 6 and 7 in
Table
1.9
b
The parameter a in BRE may reflect the number of enzymes forming an
enzyme complex.
If this conjecture is right, transcriptosomes and degradosomes
together may contain over 10
2
individual enzymes, just as a quantum dot contains 10
2
-10
3
individual atoms (see Table
4.7
)
c
The classes (or bins) of the quantitative measure of the similarity between two RNA trajectories
