Environmental Engineering Reference
In-Depth Information
Table 7.10 A Summary of Effects of Human Exposure to PBDEs
System
affected
Adverse effect reported
References
1. Thyroid
• Disruption of thyroid hormone,
homeostasis
Darnerud et al.
(2001)
Hallgren and
Darnerud (1998)
Turyk et al. (2008)
• Reduced levels of thyroxin in
blood
Meeker et al.
(2009b)
2. Male
reproductive
system
• Reduced testis size and reduced
semen quality
Akutsu et al.
(2008)
Main et al. (2007)
• Increased risk of
cryptorchidism
3. Female
reproductive
system
• Unsuccessful or complicated
pregnancies
• Decreased fertility
Morreale de
Escobar et al.
(2000)
Harley et al. (2010)
4. Cancer
(human)
• Increased risk of testicular
cancer (2nd generation)
Meeker et al.
(2007)
5. Hepatic effects • Liver enlargement, sometimes
with degenerative changes
Zhou et al. (2001)
Zhou et al. (2002)
An interesting recent study (Gaylor et al., 2012) showed house crickets
( Acheta domesticus ) provided with free access to polyurethane foam with
8.7 wt. % of penta-BDE as well as uncontaminated food for 28 days
accumulated substantial body burdens of 13.4 mg/kg of EDC. Even with
food and water available ad libitum , the crickets still ingested
PBDE-contaminatedfoamandshowednoapparentdistressdespitethehigh
body burdens. However, effects on the larval stages and the role of these as
vectors for PBDE transfer have not been investigated.
 
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