Environmental Engineering Reference
In-Depth Information
Figure 7.1
Approximate mean BPA concentrations in baby bottles and
canned food or beverages compared to that in plasma and the placenta
(Schönfelder et al., 2002).
Sources: Canned food data is based on Cao et al.'s (2011) study. Canned
beverage data is from Geens et al.'s (2010) study. Baby bottle data are variable
because of the different temperatures, leach times, and simulants used.
7.2.2 Effects of Exposure to BPA
Adverse health effects of exposure to BPA have been reported at a range of
doses including a substantial literature on effects at doses well below the
reference dose of 50 µg/kg body weight/day deemed “safe” by the USEPA.
Most of the data, however, are based on animal model studies. A detailed
discussion of these effects and the possible mechanisms of toxicity involved
are beyond the scope of this chapter. However, the major effects are
