Validating AIM-Based Instrumentation and Associated Measurement Techniques - Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products - page 293

Fig. 10.13 Photomicrograph
of displaced Brij 35
surfactant on collection plate
for the second impaction
stage of the AIM-pHRT
impactor ( From [ 27 ]— used
with permission )
Fig. 10.14 Comparative measures of impactor-sized subfractions by ACI with measures of CPF,
FPF, and EPF after modifying second impaction stage of AIM-pHRT CI with Brij-35-soaked filter
( From [ 27 ]— used with permission )
reduced systems. Despite this finding, measurement time gains were found to be
significant; analysis with the abbreviated systems taking around 30% of the time
consumed using the ACI. This finding of more rapid determinations is a consistent
trend across other reported studies to be discussed later in this chapter.