The AIM and EDA Concepts: Why They Are Needed and How They Fit Together - Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products - page 119

Fig. 5.3 Two streams for laboratory measurements of OIP aerosol performance
Fig. 5.4 Purposes for making CI-based measurements in either OIP quality control or to predict
HRT deposition
the multistage CI, although adequate for size-fractionating aerosol particles, is
not an analogue of the particle deposition processes that take place in the HRT
[ 17 ] (see Chap. 2 ) .
Early on in the process of developing the two concepts, an understanding devel-
oped that there are two fundamentally different reasons why OIPs are evaluated in
the laboratory (Fig. 5.3 ). Each stream can be further subdivided into a series of
different purposes (Fig. 5.4 ).