Biology Reference
In-Depth Information
Fig. 2 The standard version of the program, DIALIGN 2.2.1, at BiBiServ. Sequences can be uploaded or pasted
into a window in FASTA format. Only one parameter needs to be specified, namely a threshold T for the quality
of local pairwise alignments (fragments) that are incorporated into the final MSA
the same way by both aligners. (2) Alternatively, two MSAs of the
same sequence that may have been calculated by arbitrary methods
can be uploaded for comparison.
6
Program Availability at GOBICS and BiBiServ
Various versions of DIALIGN are available to the research
community through web servers; in addition, the program code is
freely available. Since much of the program development has been
done at
University of Bielfeld
, Germany, the standard version of
DIALIGN
is available from
Bielefeld University Bioinformatics
Server (BiBiServ)
(
http://bibiserv.techfak.uni-bielefeld.de/
)
(Fig.
1
). Here, it is also possible to run
DIALIGN 2.2.1
through
an easy-to-use web interface. Fig.
2
shows the web interface at
BiBiserv.
When I moved to
University of G¨ttigen
, Germany, in 2002, the
main development work on
DIALIGN
continued there, and a
