Biomedical Engineering Reference
In-Depth Information
protein
acid
acid
+
PrtP
alkaline
biosynthesis
-
oligopeptides
ATP
Amino acids
H
+
Fig. 7.5
Proteolytic system of lactic acid bacteria (Adapted from [
44
] ).
PrtP
, Cell- envelope-
associated proteinase (CEP)
PepE
PepO
PepF
Endopeptidase
Ser
Phe
PepN (general aminopeptidase)
PepC (general aminopeptidase)
PepA (narrow specificity aminopeptidase)
Glu/Asp
Prolyl-oligopeptidase
Pro
PepP (aminopeptidase P)
Pro
PepL (leucyl aminopeptidase)
Leu
Leu
PepI (proline iminopeptidase)
Exopeptidase
Pro
PepV (general dipeptidase)
Carboxypeptidase
Carboxypeptidase P / Prolyl-carboxypeptidase
Pro
PepX (X- prolyl dipeptidyl aminopeptidase)
Pro
Dipeptidyl-peptidase IV
Gly
Ile
Pro
Gly
Dipeptidyl-peptidase II
Leu
Pro
Gly
PepQ (prolidase)
PepR (prolinase)
Pro
Pro
PepT (tripeptidase)
Fig. 7.6
Peptidase system of lactic acid bacteria (e.g.
Lactobacillus sanfranciscensis
) and substrate
speci fi city (Adapted from [
50
] )
