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Table 2 Comparative leukocyte detection performance of the BSV approach, the IO method, the
Wang algorithm, the BGA detector and the proposed DE method over the data set which contains
30 images and 426 leukocytes
Leukocyte type
Method
Leukocytes
detected
Missing
False
alarms
DR
(%)
FAR
(%)
Bright leukocytes
(287)
BSV [3]
130
157
84
45.30
29.27
IO [4]
227
60
73
79.09
25.43
Wang [5]
231
56
60
80.49
20.90
GAB [16]
220
67
22
76.65
7.66
DE-based
281
6
11
97.91
3.83
Dark leukocytes
(230)
BSV [3]
105
125
59
46.65
25.65
IO [4]
183
47
61
79.56
26.52
Wang [5]
196
34
47
85.22
20.43
GAB [16]
179
51
23
77.83
10.00
DE-based
227
3
3
98.70
1.30
Overall (517)
BSV [3]
235
282
143
45.45
27.66
IO [4]
410
107
134
79.30
25.92
Wang [5]
427
90
107
82.59
20.70
GAB [16]
399
118
45
77.18
8.70
DE-based
508
9
14
98.26
2.71
and data acquisition systems. Therefore, the detection results depend on the algo-
rithm
s ability to cope with different kinds of noises. In order to demonstrate the
robustness in the WBC detection, the proposed DE approach is compared to the
BSV approach, the IO method, the Wang algorithm and the BGA detector under
noisy environments. In the test, two different experiments have been studied.
The
'
first inquest explores the performance of each algorithm when the detection
task is accomplished over images corrupted by Salt and Pepper noise. The second
experiment considers images polluted by Gaussian noise. Salt and Pepper and
Gaussian noise are selected for the robustness analysis because they represent the
most compatible noise types commonly found in images of blood smear (Landi and
Piccolomini 2012 ). The comparison considers the complete set of 50 images pre-
sented in Sect. 6.1 containing 517 leukocytes which have been detected and
counted by a human expert.
The added noise is produced by MatLab
©
, considering two noise levels of 5 and
10 % for Salt and Pepper noise whereas
10 are used for the case of
Gaussian noise. Such noise levels, according to (Tapiovaara and Wagner 1993 ),
correspond to the best trade of between detection dif
r ¼
5and
r ¼
culty and the real existence in
medical imaging. If higher noise levels are used then the detection process would be
unnecessarily complicated without representing a feasible image condition.
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