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Figure 2 Active site of acetylene hydratase. The W ion is octahedrally coordinated by the
two MGD cofactors (P and Q), Cys141, and a water molecule. Asp13 forms a short hydrogen
bond to the water molecule. Element colors: W in cyan, O in red, S in yellow, N in blue, C in gray,
P in orange.
Figure 3 View down the access funnel towards the active site of AH. The six amino acid residues
(Ile14, Ile113, Ile142, Trp179, Trp293, and Trp472) of the hydrophobic ring are represented as
green spheres. W in cyan, O in red, S in yellow, N in blue, C in gray, P in orange, and Fe in brown.
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