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346. Lorico A, Rappa G, Finch RA, Yang D, Flavell RA, Sartorelli AC. 1997. Disruption
of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to
etoposide (VP-16) and increased levels of glutathione. Cancer Res 57: 5238-5242.
347. Park S, Sinko PJ. 2005. P-Glycopotein and multidrug resistance-asociated proteins limit
the brain uptake of saquinavir in mice. J Pharmacol Exp Ther 312: 1249-1256.
348. Lorico A, Rappa G, Flavell RA, Sartorelli AC. 1996. Double knockout of the MRP gene
leads to increased drug sensitivity in vitro. Cancer Res 56: 5351-5355.
349. Allen JD, Brinkhuis RF, van Deemter L, Wijnholds J, Schinkel AJ. 2000. Extensive con-
tribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance.
Cancer Res 60: 5761-5766.
350. Suzuki H, Sugiyama Y. 2002. Single nucleotide polymorphisms in multidrug resistance
associated protein 2 (MRP2/ABCC2): its impact on drug disposition. Adv Drug Deliv
Rev 54: 1311-1331.
351. Elferink RO, Groen AK. 2002. Genetic defects in hepatobiliary transport. Biochim Bio-
phys Acta 1586: 129-145.
352. Paulusma CC, Bosma PJ, Zaman GJ, Bakker CT, Otter M, Scheffer GL, Scheper RJ, Borst
P, Oude Elferink RP. 1996. Congenital jaundice in rats with a mutation in a multidrug
resistance-associated protein gene. Science 271: 1126-1128.
353. Paulusma CC, Kool M, Bosma PJ, Scheffer GL, ter Borg F, Scheper RJ, Tytgat GN, Borst
P, Baas F, Oude Elferink RP. 1997. A mutation in the human canalicular multispecific
organic anion transporter gene causes the Dubin-Johnson syndrome. Hepatology 25:
1539-1542.
354. Paulusma CC, Oude Elferink RP. 1997. The canalicular multispecific organic anion trans-
porter and conjugated hyperbilirubinemia in rat and man. J Mol Med 75: 420-428.
355. Ito K, Suzuki H, Hirohashi T, Kume K, Shimizu T, Sugiyama Y. 1997. Molecular cloning
of canalicular multispecific organic anion transporter defective in EHBR. Am J Physiol
272: G16-G22.
356. Jansen PL, Peters WH, Lamers WH. 1985. Hereditary chronic conjugated hyperbiliru-
binemia in mutant rats caused by defective hepatic anion transport. Hepatology 5: 573-
579.
357. Itoda M, Saito Y, Soyama A, Saeki M, Murayama N, Ishida S, Sai K, Nagano M, Suzuki H,
Sugiyama Y, Ozawa S, Sawada J. 2002. Polymorphisms in the ABCC2 (cMOAT/MRP2)
gene found in 72 estabilished cell lines derived from Japanese individuals: an association
between single-nucleotide polymorphisms in the 5
-untranslated region and exon 28. Drug
Metab Dispos 30: 363-364.
358. Bosch TM, Doodeman VD, Smits PH, Meijerman I, Schellens JH, Beijnen JH. 2006.
Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug
transpoters in a Dutch population. Mol Diagn Ther 10: 175-185.
359. Shoda J, Kano M, Oda K, Kamiya J, Nimura Y, Suzuki H, Sugiyama Y, Miyazaki H,
Todoroki T, Stengelin S, et al. 2001. The expression levels of plasma membrane trans-
porters in the cholestatic liver of patients undergoing biliary drainage and their association
with the impairment of biliary secretory function. Am J Gastroenterol 96: 3368-3378.
360. Zollner G, Fickert P, Zenz R, Fuchsbichler A, Stumptner C, Kenner L, Ferenci P, Stauber
RE, Krejs GJ, Denk H, Zatloukal K, Trauner M. 2001. Hepatobiliary transporter expres-
sion in percutaneous liver biopsies of patients with cholestatic liver diseases. Hepatology
33: 633-646.
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