Biomedical Engineering Reference
In-Depth Information
5. Nada S, Yagi T, Takeda H, Tokunaga T, Nakagawa H, Ikawa Y, Okada M, Aizawa S.
1993. Constitutive activation of Src family kinases in mouse embryos that lack Csk. Cell
73:1125-1135.
6. Yagi T, Ikawa Y, Yoshida K, Shigetani Y, Takeda N, Mabuchi I, Yamamoto T, Aizawa
S. 1990. Homologous recombination at c-fyn locus of mouse embryonic stem cells with
use of diphtheria toxin A-fragment gene in negative selection. Proc Natl Acad Sci USA
87:9918-9922.
7. Kubo Y, Sekiya S, Ohigashi M, Takenaka C, Tamura K, Nada S, Nishi T, Yamamoto A,
Yamaguchi A. 2005. ABCA5 resides in lysosomes, and ABCA5 knockout mice develop
lysosome disease-like symptoms. Mol Cell Biol 25:4138-4149.
8. Hasuwa H, Kaseda K, Einarsdottir T, Okabe M. 2002. Small interfering RNA and gene
silencing in transgenic mice and rats. FEBS Lett 532:227-230.
9. Tiscornia G, Singer O, Ikawa M, Verma IM. 2003. A general method for gene knockdown
in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci
USA 100:1844-1848.
10. Liu F, Song Y, Liu D. 1999. Hydrodynamics-based transfection in animals by systemic
administration of plasmid DNA. Gene Ther 6:1258-1266.
11. Kobayashi N, Nishikawa M, Takakura Y. 2005. The hydrodynamics-based procedure for
controlling the pharmacokinetics of gene medicines at whole body, organ and cellular
levels. Adv Drug Deliv Rev 57:713-731.
12. Kobayashi N, Nishikawa M, Hirata K, Takakura Y. 2004. Hydrodynamics-based pro-
cedure involves transient hyperpermeability in the hepatic cellular membrane: impli-
cation of a nonspecific process in efficient intracellular gene delivery. J Gene Med
6:584-592.
13. Kobayashi N, Hirata K, Chen S, Kawase A, Nishikawa M, Takakura Y. 2004. Hepatic
delivery of particulates in the submicron range by a hydrodynamics-based procedure:
implications for particulate gene delivery systems. J Gene Med 6:455-463.
14. Kobayashi N, Matsui Y, Kawase A, Hirata K, Miyagishi M, Taira K, Nishikawa M,
Takakura Y. 2004. Vector-based in vivo RNA interference: dose- and time-dependent sup-
pression of transgene expression. J Pharmacol Exp Ther 308:688-693.
15. Matsui Y, Kobayashi N, Nishikawa M, Takakura Y. 2005. Sequence-specific suppression
of mdr1a/1b expression in mice via RNA interference. Pharm Res 22:2091-2098.
16. Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol
CA, van der Valk MA, Robanus-Maandag EC, te Riele HP, et al. 1994. Disruption of the
mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to
increased sensitivity to drugs. Cell 77:491-502.
17. Jonker JW, Buitelaar M, Wagenaar E, van der Valk MA, Scheffer GL, Scheper RJ, Plosch
T, Kuipers F, Elferink RP, Rosing H, Beijnen JH, Schinkel AH. 2002. The breast cancer
resistance protein protects against a major chlorophyll-derived dietary phototoxin and
protoporphyria. Proc Natl Acad Sci USA 99:15649-15654.
18. Murata M, Tamai I, Sai Y, Nagata O, Kato H, Sugiyama Y, Tsuji A. 1998. Hepatobiliary
transport kinetics of HSR-903, a new quinolone antibacterial agent. Drug Metab Dispos
26:1113-1119.
19. Sasabe H, Terasaki T, Tsuji A, Sugiyama Y. 1997. Carrier-mediated hepatic uptake of
quinolone antibiotics in the rat. J Pharmacol Exp Ther 282:162-171.
Search WWH ::
Custom Search