Biomedical Engineering Reference
In-Depth Information
To Study Drug Transporters · · ·
In vivo Comparison Study
~Importance & Role in the Body
· Knockout & Knockdown Animals
· Integration Plot
· Loop Method
· Many In Vitro methods
· Pharmacokinetic Parameters · · · · ·
Primary Cells, Model Cells & Vesicles
~Simple & Rapid Evaluation
· Isolated Primary Cells
· Polar Cell Lines
· Immortalized Cells · · · · ·
Isolated Tissue
~Transport Properties in Organ
· Ussing-type Chamber Method
· Everted Sac Method
· Organ Slices
· Membrane Vesicles · · · · ·
Expression Systems
~Toward Molecular Identification
· Cultured Cells
· Xenopus laevis Oocytes
· Membrane Vesicles · · · · ·
Interaction & Inhibition Study
~Transport Specificity
& Avoidance of Side Effect
· Inhibition Profile
· Promoter Assay
· Gel Shift Assay
· Immunoprecipitation
· Biotinylation Study
 
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