DRUG TRANSPORT IN THE KIDNEY - Drug Transporters: Molecular Characterization and Role in Drug Disposition - page 483

transporter family that is almost exclusively expressed in the kidney. J Biol Chem
272:6471-6478.
25. Shimada H, Moewes B, Burckhardt G. 1987. Indirect coupling to Na + of p -aminohippuric
acid uptake into rat renal basolateral membrane vesicles. Am J Physiol 253:F795-F801.
26. Sekine T, Cha SH, Endou H. 2000. The multispecific organic anion transporter (OAT)
family. Pflugers Arch 440:337-350.
27. Hosoyamada M, Sekine T, Kanai Y, Endou H. 1999. Molecular cloning and functional
expression of a multispecific organic anion transporter from human kidney. Am J Physiol
276:F122-F128.
28. Bahn A, Prawitt D, Buttler D, Reid G, Enklaar T, Wolff NA, Ebbinghaus C, Hillemann
A, Schulten HJ, Gunawan B, et al. 2000. Genomic structure and in vivo expression of
the human organic anion transporter 1 (hOAT1) gene. Biochem Biophys Res Commun
275:623-630.
29. Bahn A, Ebbinghaus C, Ebbinghaus D, Ponimaskin EG, F uzesi L, Burckhardt G, Hagos
Y. 2004. Expression studies and functional characterization of renal human organic anion
transporter 1 isoforms. Drug Metab Dispos 32:424-430.
30. Simonson GD, Vincent AC, Roberg KJ, Huang Y, Iwanij V. 1994. Molecular cloning and
characterization of a novel liver-specific transport protein. J Cell Sci 107:1065-1072.
31. Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H. 1998.
Identification of multispecific organic anion transporter 2 expressed predominantly in the
liver. FEBS Lett 429:179-182.
32. Morita N, Kusuhara H, Sekine T, Endou H, Sugiyama Y. 2001. Functional characterization
of rat organic anion transporter 2 in LLC-PK1 cells. J Pharmacol Exp Ther 298:1179-
1184.
33. Enomoto A, Takeda M, Shimoda M, Narikawa S, Kobayashi Y, Kobayashi Y, Yamamoto
T, Sekine T, Cha SH, Niwa T, Endou H. 2002. Interaction of human organic anion trans-
porters 2 and 4 with organic anion transport inhibitors. J Pharmacol Exp Ther 301:
797-802.
34. Kobayashi Y, Ohshiro N, Shibusawa A, Sasaki T, Tokuyama S, Sekine T, Endou H,
Yamamoto T. 2002. Isolation, characterization and differential gene expression of multi-
specific organic anion transporter 2 in mice. Mol Pharmacol 62:7-14.
35. Takeda M, Khamdang S, Narikawa S, Kimura H, Kobayashi Y, Yamamoto T, Cha SH,
Sekine T, Endou H. 2002. Human organic anion transporters and human organic cation
transporters mediate renal antiviral transport. J Pharmacol Exp Ther 300:918-924.
36. Kimura H, Takeda M, Narikawa S, Enomoto A, Ichida K, Endou H. 2002. Human or-
ganic anion transporters and human organic cation transporters mediate renal transport
of prostaglandins. J Pharmacol Exp Ther 301:293-298.
37. Babu E, Takeda M, Narikawa S, Kobayashi Y, Yamamoto T, Cha SH, Sekine T, Sak-
thisekaran D, Endou H. 2002. Human organic anion transporters mediate the transport of
tetracycline. Jpn J Pharmacol 88:69-76.
38. Kusuhara H, Sekine T, Utsunomiya-Tate N, Tsuda M, Kojima R, Cha SH, Sugiyama Y,
Kanai Y, Endou H. 1999. Molecular cloning and characterization of a new multispecific
organic anion transporter from rat brain. J Biol Chem 274:13675-13680.
39. Brady KP, Dushkin H, Fornzler D, Koike T, Magner F, Her H, Gullans S, Segre GV,
Green RM, Beier DR. 1999. A novel putative transporter maps to the osteosclerosis (oc)
mutation and is not expressed in the oc mutant mouse. Genomics 56:254-261.