DRUG TRANSPORT IN THE BRAIN - Drug Transporters: Molecular Characterization and Role in Drug Disposition - page 459

332. Lee G, Piquette-Miller M. 2003. Cytokines alter the expression and activity of the
multidrug resistance transporters in human hepatoma cell lines; analysis using RT-PCR
and cDNA microarrays. J Pharm Sci 92:2152-2163.
333. Ronaldson PT, Bendayan R. 2006. HIV-1 viral envelope glycoprotein gp120 triggers an
inflammatory response in cultured rat astrocytes and regulates the functional expression
of P-glycoprotein. Mol Pharmacol 70:1087-1098.
334. Gollapudi S, Gupta S. 1990. Human immunodeficiency virus I-induced expression of
P-glycoprotein. Biochem Biophys Res Commun 171:1002-1007.
335. Andreana A, Aggarwal S, Gollapudi S, Wien D, Tsuruo T, Gupta S. 1996. Abnormal
expression of a 170-kilodalton P-glycoprotein encoded by MDR1 gene, a metabol-
ically active efflux pump, in CD4 + and CD8 + T cells from patients with human
immunodeficiency virus type 1 infection. AIDS Res Hum Retrovir 12:1457-1462.
336. Malorni W, Lucia MB, Rainaldi G, Cauda R, Cianfriglia M, Donelli G, Ortona L. 1998.
Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell
subsets from healthy donors and HIV-infected patients. Haematologica 83:13-20.
337. Meaden ER, Hoggard PG, Maher B, Khoo SH, Back DJ. 2001. Expression of P-
glycoprotein and multidrug resistance-associated protein in healthy volunteers and
HIV-infected patients. AIDS Res Hum Retrovir 17:1329-1332.
338. Hayashi K, Pu H, Andras IE, Eum SY, Yamauchi A, Hennig B, Toborek M. 2006.
HIV-TAT protein upregulates expression of multidrug resistance protein 1 in the
blood-brain barrier. J Cereb Blood Flow Metab 26:1052-1065.
339. Hayashi K, Pu H, Tian J, Andras IE, Lee YW, Hennig B, Toborek M. 2005. HIV-Tat
protein induces P-glycoprotein expression in brain microvascular endothelial cells. J
Neurochem 93:1231-1241.
340. Deeks SG, Smith M, Holodniy M, Kahn JO. 1997. HIV-1 protease inhibitors. A review
for clinicians. JAMA 277:145-153.
341. Lee CG, Gottesman MM, Cardarelli CO, Ramachandra M, Jeang KT, Ambudkar SV,
Pastan I, Dey S. 1998. HIV-1 protease inhibitors are substrates for the MDR1 multidrug
transporter. Biochemistry 37:3594-3601.
342. Williams GC, Liu A, Knipp G, Sinko PJ. 2002. Direct evidence that saquinavir is trans-
ported by multidrug resistance-associated protein (MRP1) and canalicular multispecific
organic anion transporter (MRP2). Antimicrob Agents Chemother 46:3456-3462.
343. Reid G, Wielinga P, Zelcer N, de Haas M, van Deemter L, Wijnholds J, Balzarini
J, Borst P. 2003. Characterization of the transport of nucleoside analog drugs by the
human multidrug resistance proteins MRP4 and MRP5. Mol Pharmacol 63:1094-
1103.
344. Guo Y, Kotova E, Chen ZS, Lee K, Hopper-Borge E, Belinsky MG, Kruh GD.
2003. MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux
pump and a resistance factor for fluoropyrimidines 2 ,3 -dideoxycytidine and 9 -(2 -
phosphonylmethoxyethyl)adenine. J Biol Chem 278:29509-29514.
345. Wang X, Furukawa T, Nitanda T, Okamoto M, Sugimoto Y, Akiyama S, Baba M. 2003.
Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1
nucleoside reverse transcriptase inhibitors. Mol Pharmacol 63:65-72.
346. Wang X, Baba M. 2005. The role of breast cancer resistance protein (BCRP/ABCG2)
in cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors. Antivir Chem
Chemother 16:213-216.